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Laser trap measurements show that mechanical work output from curling protofilaments is enhanced by adding magnesium, and that yeast microtubules generate larger and more energetic working strokes than bovine microtubules.

Pairs of spinal cord neurons arising from a shared progenitor get input from and make outputs to mostly different synaptic partners.

In the mouse cerebellum, the number of branched synapses is reduced in half after sleep compared to after wake.

Combining transcriptomic data with the analysis of large genome-wide association studies helps identify genes that are likely important for regulating bone mineral density.

A new technology to study physiology and cognition elevates African turquoise killifish as a model organism for studies of aging in vertebrates.

The comparison of three ciliate species that share complex pathways for natural genome editing allows capture of intermediate states in the acquisition of scrambled genes and elucidating a pathway for the origin and evolution of extremely rearranged chromosomes.

Prefrontal PV interneuron activity during development is necessary for prefrontal circuit maturation, supporting adult prefrontal network function and cognitive flexibility.

Levels of the metabolite NMN, the precursor of NAD⁺, determine whether dSarm-mediated axon death signaling is activated and injury-induced axon degeneration executed in the fruit fly Drosophila.

Human-like color categories emerge in a Deep Neural Network trained only on object recognition.

Mouse deficiencies for the dynein-binding protein LIS1 reveal different cell division mechanisms across T-cell subsets.