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Latest articles

1. 1. Computational and Systems Biology

   Genetics: From mouse to human

   Arya Mani

   A deep analysis of multiple genomic datasets reveals which genetic pathways associated with atherosclerosis and coronary artery disease are shared between mice and humans.
2. 1. Epidemiology and Global Health

   Sleep: Another benefit of regular sleep

   Tianyi Huang

   A large observational study has found that irregular sleep-wake patterns are associated with a higher risk of overall mortality, and also mortality from cancers and cardiovascular disease.
3. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   Transcription: A hub of activity

   Virginia L Pimmett, Mounia Lagha

   Imaging experiments reveal the complex and dynamic nature of the transcriptional hubs associated with Notch signaling.
4. 1. Cell Biology

   Trans-Golgi Network: Sorting secretory proteins

   Anup Parchure, Julia von Blume

   A receptor protein called TGN46 has an important role in sorting secretory proteins into vesicles going to different destinations inside cells.
5. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Antibody Specificity: A strong case for third-party testing

   Fridtjof Lund-Johansen

   A strategy to identify high-quality commercially available antibodies for research reveals extensive use of non-specific antibodies and offers solutions for future large-scale testing.
6. 1. Neuroscience

   Anesthesia: Putting early sensory neurons to sleep

   Julia Fadjukov, Gregory Schwartz

   Neurons that transmit information from the retina to other parts of the brain are more affected by anesthesia than previously thought.
7. 1. Evolutionary Biology
   2. Neuroscience

   Cerebellum: Folding into shape

   Héloïse de Vareilles

   A new computational tool provides insights into the structure of the cerebellum in mammals.
8. 1. Medicine

   Cardiology: A new strategy for cardiac protection

   Esmaa Bouhamida, Hina W Chaudhry

   It may be possible to treat cardiac hypertrophy and injury by using drugs that inhibit a protein called SIRT2.
9. 1. Evolutionary Biology

   Genetics: A colourful duplication

   Violaine Llaurens

   A genetic duplication event during evolution allowed male wood tiger moths to have either yellow or white patterns on their wings.
10. 1. Genetics and Genomics
    2. Neuroscience

    Feeding: How specific molecules can lead to overeating

    María Gabriela Blanco, Diego Rayes

    A molecular pathway involving compounds found in processed foods and biogenic amines increases food intake and aging in the roundworm C. elegans.