eLife Science Digests

Cutting jargon and putting research in context, digests showcase some of the latest articles published in eLife.

Latest

  1. Regulating LRRK2

    A newly discovered Rab12-dependent mechanism helps to recruit and increase the activity of an enzyme involved in Parkinson’s disease at the membrane of lysosomes.

  2. Investigating antifungal tolerance

    A refined single-cell sequencing technique provides insight into how pathogenic fungi respond to drugs.

  3. Revealing cell death differences

    The multiple pathways that can trigger cell death in response to infection are not interchangeable and have specific outcomes in different cell types.

  4. A non-winning combination

    Malaria parasites can rapidly evolve resistance to treatment containing two different drugs that both inhibit the DHODH enzyme.

  5. Fear disconnects

    The neurons and brain regions involved in storing and retrieving fear memories connect together differently when remembering more traumatic experiences.

  6. Old drugs, new tricks

    A family of drugs used to treat patients with osteoporosis may be linked with a reduced risk of COVID-19, a preliminary study shows.

  7. Obesity and grey matter

    Analysing 30,000 MRI scans of the human brain provides new insights into the connections between obesity and parts of the brain involved in cognition.

  8. Sperm heads and tails

    Male mice that are unable to produce two cytoskeleton proteins unique to sperm are infertile.
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