Browse our latest Computational and Systems Biology articles

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    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Quantitative analyses of T cell motion in tissue reveals factors driving T cell search in tissues

    David J Torres, Paulus Mrass ... Judy L Cannon
    The analysis of T cell movement in multiple tissues (lymph node, villi, and lung under two different inflammatory conditions) sheds new light on how T cells navigate different tissue environments to improve immunity and search processes.
    1. Cell Biology
    2. Computational and Systems Biology

    Reprogramming of cardiac phosphoproteome, proteome and transcriptome confers resilience to chronic adenylyl cyclase-driven stress

    Jia-Hua Qu, Khalid Chakir ... Edward G. Lakatta
    1. Computational and Systems Biology

    Multicellular factor analysis of single-cell data for a tissue-centric understanding of disease

    Ricardo Omar Ramirez Flores, Jan David Lanzer ... Julio Saez-Rodriguez
    1. Cancer Biology
    2. Computational and Systems Biology

    Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records

    Jessica Xin Hjaltelin, Sif Ingibergsdóttir Novitski ... Søren Brunak
    A comprehensive comparison of the two types of pancreatic cancer symptom trajectories can in combination leverage a fuller potential of large health data and ultimately aid the detection of early risk factors for pancreatic cancer.
    1. Computational and Systems Biology
    2. Neuroscience

    Neuroimaging and behavioral evidence that violent video games exert no negative effect on human empathy for pain and emotional reactivity to violence

    Lukas Leopold Lengersdorff, Isabella C Wagner ... Claus Lamm
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Computational analysis of long-range allosteric communications in CFTR

    Ersoy Ayca, Altintel Bengi ... Lewinson Oded
    1. Computational and Systems Biology
    2. Neuroscience

    Endotaxis: A neuromorphic algorithm for mapping, goal-learning, navigation, and patrolling

    Tony Zhang, Matthew Rosenberg ... Markus Meister
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Systems genetics approaches for understanding complex traits with relevance for human disease

    Hooman Allayee, Charles R Farber ... Aldons J Lusis
    Systems genetics is a powerful approach that links DNA variation to complex clinical and physiological traits through the integration of intermediate phenotypes, such as RNA, protein, and metabolite levels.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    No Ramp Needed: Spandrels, Statistics, and a Slippery Slope

    Richard Sejour, Janet Leatherwood ... Bruce Futcher
    1. Computational and Systems Biology
    2. Developmental Biology

    Diversity in Notch ligand-receptor signaling interactions

    Rachael Kuintzle, Leah A. Santat, Michael B. Elowitz
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