Computational and Systems Biology

Latest articles

1. 1. Computational and Systems Biology

   Homeostasis, injury and recovery dynamics at multiple scales in a self-organizing mouse intestinal crypt

   Louis Gall, Carrie Duckworth ... Carmen Pin
2. 1. Computational and Systems Biology
   2. Genetics and Genomics

   Comparative Interactome Analysis of α-arrestin Families in Human and Drosophila

   Kyung-Tae Lee, Inez K.A. Pranoto ... Jin-Wu Nam
3. 1. Computational and Systems Biology

   Genetics: From mouse to human

   Arya Mani

   A deep analysis of multiple genomic datasets reveals which genetic pathways associated with atherosclerosis and coronary artery disease are shared between mice and humans.
4. 1. Computational and Systems Biology

   Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse

   Zeyneb Kurt, Jenny Cheng ... Xia Yang

   Cross-species multiomics network modeling revealed tissue-specific regulatory genes, pathways, and networks shared between mouse and human or unique to each species for atherosclerosis and coronary artery disease.
5. 1. Computational and Systems Biology
   2. Microbiology and Infectious Disease

   Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compounds

   Vanessa Dumeaux, Samira Massahi ... Michael T Hallett

   Candida albicans cells respond in two distinct ways to fluconazole exposure where cells enter the Ribo-dominant state characterized by an upregulation of ribosomal-related proteins and processes, or cells enter the Stress-dominant state characterized by the upregulation of stress responses.
6. 1. Cell Biology
   2. Computational and Systems Biology

   Neural network emulation of the human ventricular cardiomyocyte action potential: a tool for more efficient computation in pharmacological studies

   Thomas Grandits, Christoph M. Augustin ... Alexander Jung
7. 1. Computational and Systems Biology

   Detection of new pioneer transcription factors as cell-type specific nucleosome binders

   Yunhui Peng, Wei Song ... Anna R. Panchenko
8. 1. Biochemistry and Chemical Biology
   2. Computational and Systems Biology

   Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting

   Ian R Outhwaite, Sukrit Singh ... Markus A Seeliger
9. 1. Computational and Systems Biology
   2. Physics of Living Systems

   Beta-cell intrinsic dynamics rather than gap junction structure dictates subpopulations in the islet functional network

   Jennifer K Briggs, Anne Gresch ... Richard KP Benninger
10. 1. Computational and Systems Biology
    2. Neuroscience

    Deciphering the Genetic Code of Neuronal Type Connectivity: A Bilinear Modeling Approach

    Mu Qiao