Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression

   The transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis and cytoplasmic decay

   M. Kelbert, T. Jordan ... M. Choder
2. 1. Chromosomes and Gene Expression

   Alternative end-joining results in smaller deletions in heterochromatin relative to euchromatin

   Jacob M. Miller, Sydney Prange ... Irene Chiolo
3. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Single cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveals heterogeneity of endothelial subtype and response to activating perturbations

   Maria L. Adelus, Jiacheng Ding ... Casey E. Romanoski
4. 1. Chromosomes and Gene Expression
   2. Neuroscience

   Avoiding false discoveries in single-cell RNA-seq by revisiting the first Alzheimer’s disease dataset

   Alan E Murphy, Nurun Fancy, Nathan Skene

   Reanalysis reveals the impact of quality control and differential analysis methods on the discovery of disease-associated genes on the first Alzheimer's disease single-nucleus RNA-seq dataset.
5. 1. Chromosomes and Gene Expression

   Regulation of Chromatin Architecture by Transcription Factor Binding

   Stephanie Portillo-Ledesma, Suckwoo Chung ... Tamar Schlick
6. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Chromosome-specific maturation of the epigenome in the Drosophila male germline

   James T Anderson, Steven Henikoff, Kami Ahmad

   Chromatin profiling of Drosophila testes reveals activation of the transcriptional program of the germline, widespread changes in RNA polymerase progression, and the absence of chromosomal regulation across the X chromosome.
7. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   Transcription: A hub of activity

   Virginia L Pimmett, Mounia Lagha

   Imaging experiments reveal the complex and dynamic nature of the transcriptional hubs associated with Notch signaling.
8. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes

   Abdoulie O Touray, Rishi Rajesh ... Igor Cestari

   Nuclear phosphoinositide signaling controls telomeric gene repression and activation essential for switching expression of surface antigen genes and thus antigenic variation.
9. 1. Chromosomes and Gene Expression

   Integrative analysis of DNA replication origins and ORC/MCM binding sites in human cells reveals a lack of overlap

   Mengxue Tian, Zhenjia Wang ... Chongzhi Zang
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes

    Baira Godneeva, Maria Ninova ... Alexei Aravin

    Bonus, the Drosophila TIF1 factor, functions as a repressor of tissue-specific genes in the germline, emphasizing an important function of SUMOylation in transcriptional regulation.