The ability of the therapeutic glucagon-like peptide-1 receptor agonist liraglutide to promote weight loss is partly dependent on signaling via PKA-dependent phosphorylation of the mTORC1 regulator protein Raptor.
Simon Schneider, Andjela Kovacevic ... Hubert Schorle
Cylicin 1 and Cylicin 2 are essential components of the sperm perinuclear theca and their loss results in impaired spermiogenesis and thus in infertility in mice and men.
Bronwyn A Lucas, Benjamin A Himes, Nikolaus Grigorieff
2D template matching enables a streamlined single-particle cryogenic electron microscopy workflow that can be used to discover new high-resolution structural features in molecules and complexes, such as bound ligands and drugs.
