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    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Mapping the architecture of the initiating phosphoglycosyl transferase from S. enterica O-antigen biosynthesis in a liponanoparticle

    Greg J. Dodge, Alyssa J. Anderson ... Barbara Imperiali
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Archaeal origin translation proofreader imparts multialdehyde stress tolerance to land plants

    Pradeep Kumar, Ankit Roy ... Rajan Sankaranarayanan
    1. Biochemistry and Chemical Biology

    A 2-Hydroxybutyrate- mediated feedback loop regulates muscular fatigue

    Brennan J Wadsworth, Marina Leiwe ... Randall S Johnson
    1. Biochemistry and Chemical Biology

    Unveiling the Domain-Specific and RAS Isoform-Specific Details of BRAF Regulation

    Tarah Trebino, Borna Markusic ... Zhihong Wang
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling

    Henning Mühlenbeck, Yuko Tsutsui ... Cyril Zipfel
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications

    Riham Ayoubi, Joel Ryan ... Carl Laflamme
    Open science and consensus antibody validation protocols can identify high-quality, renewable antibodies for the ~50% of the human proteome currently covered, enabling robust and reproducible biomedical research.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2

    Maya L. Bulos, Edyta M. Grzelak ... Michael J. Bollong
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Frustrated Microphase Separation Produces Interfacial Environment within Biological Condensates

    Andrew P. Latham, Longchen Zhu ... Bin Zhang
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle

    Alexis Diaz-Vegas, Soren Madsen ... James G. Burchfield
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

    Veronica Ober, George B. Githure ... Michael Boshart
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