Biochemistry and Chemical Biology

Biochemistry and Chemical Biology

eLife reviews research that gives new insights into biological molecules or uses chemical approaches to illuminate complex biological processes. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Evolution towards simplicity in bacterial small heat shock protein system

    Piotr Karaś, Klaudia Kochanowicz ... Krzysztof Liberek
    Phylogenetic and biochemical analysis reveals crucial role of two substitutions in the α–crystallin domain for development of new functionality of IbpA chaperone after the loss of paralogous IbpB in Erwiniaceae.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Indole produced during dysbiosis mediates host–microorganism chemical communication

    Rui-Qiu Yang, Yong-Hong Chen ... Cheng-Gang Zou
    In C. elegans, neuronic TRPA-1 senses bacterial accumulation by detecting indole production to up-regulate lysozyme genes via FOXO/DAF-16 in the intestine, thereby delaying microbial dysbiosis.
    1. Biochemistry and Chemical Biology

    Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein

    Yasuhiro Shinkai, Yunjie Ding ... Yoshito Kumagai
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The catalytic mechanism of the RNA methyltransferase METTL3

    Ivan Corbeski, Pablo Andrés Vargas-Rosales ... Amedeo Caflisch

Senior editors

  1. Nancy Carrasco
    Vanderbilt University School of Medicine, United States
  2. Volker Dötsch
    Goethe University, Germany
  3. Pankaj Kapahi
    Buck Institute for Research on Aging, United States
  4. See more editors