Biochemistry and Chemical Biology

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Evolutionary Biology

   Evolution towards simplicity in bacterial small heat shock protein system

   Piotr Karaś, Klaudia Kochanowicz ... Krzysztof Liberek

   Phylogenetic and biochemical analysis reveals crucial role of two substitutions in the α–crystallin domain for development of new functionality of IbpA chaperone after the loss of paralogous IbpB in Erwiniaceae.
2. 1. Biochemistry and Chemical Biology
   2. Computational and Systems Biology

   Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting

   Ian R Outhwaite, Sukrit Singh ... Markus A Seeliger
3. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Indole produced during dysbiosis mediates host–microorganism chemical communication

   Rui-Qiu Yang, Yong-Hong Chen ... Cheng-Gang Zou

   In C. elegans, neuronic TRPA-1 senses bacterial accumulation by detecting indole production to up-regulate lysozyme genes via FOXO/DAF-16 in the intestine, thereby delaying microbial dysbiosis.
4. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Comparative analysis of two Caenorhabditis elegans kinesins KLP-6 and UNC-104 reveals a common and distinct activation mechanism in kinesin-3

   Tomoki Kita, Kyoko Chiba ... Shinsuke Niwa
5. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

   Timothy A Bates, Mila Trank-Greene ... Fikadu G Tafesse
6. 1. Biochemistry and Chemical Biology

   Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein

   Yasuhiro Shinkai, Yunjie Ding ... Yoshito Kumagai
7. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   The catalytic mechanism of the RNA methyltransferase METTL3

   Ivan Corbeski, Pablo Andrés Vargas-Rosales ... Amedeo Caflisch
8. 1. Biochemistry and Chemical Biology
   2. Structural Biology and Molecular Biophysics

   The neuronal calcium sensor NCS-1 regulates the phosphorylation state and activity of the Ga chaperone and GEF Ric-8A

   Daniel Muñoz-Reyes, Levi J McClelland ... Maria Jose Sanchez-Barrena
9. 1. Biochemistry and Chemical Biology
   2. Neuroscience

   Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism

   Bernd K. Gilsbach, Franz Y. Ho ... Christian Johannes Gloeckner
10. 1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Phosphorylation, disorder, and phase separation govern the behavior of Frequency in the fungal circadian clock

    Daniyal Tariq, Nicole Maurici ... Brian R. Crane